Anti-eEF2
产品名称: Anti-eEF2
英文名称:
产品编号: 200559
产品价格: null
产品产地: 成都正能生物
品牌商标: Zen BioScience
更新时间: null
使用范围: WB
- 联系人 :
- 地址 : 中国成都高新区科园南路爱斯特大厦
- 邮编 : 610200
- 所在区域 : 四川
- 电话 : 180****2350 点击查看
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- 邮箱 : sales@zen-bioscience.com
Size 100ug
Cat code 200559
Species Cross-reactivity H
Key Application WB
Host Mouse
Antibody type Monoclonal antibody
Purified method Affinity purified
Isotype IgG2b
Molecular Weight 95kDa
Sensitivity This antibody detects endogenous levels of EEF2 and does not cross-react with related proteins.
Immunogen Purified recombinant human EEF2 protein fragments expressed in E.coli.
UniProt Number P13639
GeneBank ID NM_001961.3
Subcellular location Cytoplasm
Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername eukaryotic translation elongation factor 2;EF2;EEF-2;EF-2;elongation factor 2;polypeptidyl-tRNA translocase
Gene_symbol EF2; EF-2; EEF-2
Summary This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
UniPort summary Function Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Application Images :
Western blot detection of EEF2 in HL-60 cell lysates using EEF2 antibody (1:1000 diluted). Predicted band size:95KDa Observed band size: 95KDa.