EYA2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
EYA2抗体

EYA2抗体

商家询价

产品名称： EYA2抗体

英文名称： EYA2Antibody

产品编号： XY11314-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 EYA2抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Published applications IF, IHC Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 11314-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 11314-1-AP(EYA2 antibody) at dilution of 1:100
  • 11314-1-AP;human prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 11314-1-AP(EYA2 antibody) at dilution of 1:50 (under 10x lens)
  • 11314-1-AP;HeLa cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 11314-1-AP( EYA2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HeLa cells, mouse eye tissue, Y79 cells
Positive IHC detected in Human prostate cancer tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500
 EYA2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen EYA2 fusion protein ag1860 Full name Eyes absent homolog 2 (Drosophila)
Calculated molecular
weight		 64 kDa Observed molecular 
weight		 57 kDa
GenBank accession 
number		 BC013882 Gene ID (NCBI) 2139
Gene symbol EYA2 Synonyms EAB1, EYA2, Eyes absent homolog 2
Background EYA2抗体

EYA2, also named as EAB1, belongs to the HAD-like hydrolase superfamily and EYA family. It coactivates SIX1. The Six1-EYA2 interaction may inhibit breast cancer progression. EYA2 is required for Six1-activated TGF-beta signaling.(PMID:21706047) It may be involved in development of the eye. This protein has 3 isoforms produced by alternative splicing with the molecular weight of 59 kDa, 57 kDa and 50 kDa. It can be detected two bands of 70 kDa and 56 kDa in the neuroblastoma cells by western blot(PMID:12039049). EYA2抗体

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