HOPX抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
HOPX抗体

HOPX抗体

商家询价

产品名称： HOPX抗体

英文名称： HOPXAntibody

产品编号： XY 11419-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 HOPX抗体

Applications
In-house applications ELISA, IP, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 11419-1-AP;Mouse lungIP result of HOPX antibody (11419-1-AP for IP and Detection) with mouse lung tissue lysate.
  • 11419-1-AP;mouse lung tissuemouse lung tissue were subjected to SDS PAGE followed by western blot with 11419-1-AP( HOPX Antibody) at dilution of 1:600
Positive WB detected in Mouse lung tissue, human placenta tissue, rat lung tissue
Positive IP detected in Mouse lung
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
 HOPX抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen HOPX fusion protein ag1979 Full name HOP homeobox
Calculated molecular
weight		 73aa,8 kDa Observed molecular 
weight		 8-12kd
GenBank accession 
number		 BC014225 Gene ID (NCBI) 84525
Gene symbol HOPX Synonyms CAMEO, HOD, Homeodomain only protein, HOP, HOP homeobox, HOPX, LAGY, NECC1, OB1, Odd homeobox protein 1, SMAP31, TOTO
Background HOPX抗体

HOPX (Homeodomain-only protein) gene has various synonyms including HOD, HOP, OB1, LAGY and NECC1. The protein encoded by this gene is an unusual homeodomain protein that lacks certain conserved residues required for DNA binding. HOPX has diverse effects on cardiac growth. Manipulation of Hopx function in murine models is associated with cardiac hypertrophy, dilation and fibrosis. HOPX protein acts as an antagonist to the serum response factor (SRF), which regulates the opposing processes of cell proliferation and differentiation. Overexpression of HOPX causes cardiac hypertrophy. HOPX protein can inhibit SRF-dependent transcriptional activation by recruiting histone deacetylase (HDAC) activity. HOPX抗体

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