Detects mouse VEGF R1/Flt-1 in ELISAs and Western blots. In sandwich ELISAs,approximately 7% cross-reactivity with recombinant human VEGFR1 is observed, approximately 4%cross-reactivity with recombinant mouse (rm)VEGF164 is observed, less than 1% cross-reactivity with recombinant rat VEGF164 is observed, and less than 0.2%cross-reactivity with rmVEGFR2 and rmVEGFR3 is observed.VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 
12 months from date of receipt, -20 to -70 °C as supplied.
1 month from date of receipt, 2 to 8 °C, reconstituted.
6 months from date of receipt, -20 to -70 °C, reconstituted. *   http://www.creative-diagnostics.com/Anti-FLT1-PAb-186968-177.htm